Enflonsia was approved and recommended in 2025 by the Centers for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization Practices (ACIP) for infants born during or entering their first respiratory syncytial virus (RSV) season. Enflonsia is not a vaccine. Enflonsia is a preventative monoclonal antibody. Monoclonal antibody treatments provide pre-made antibodies that can immediately protect against RSV infection. Enflonsia is the only RSV preventative option with the same dosage administered to infants regardless of weight.
ENFLONSIA: FDA-approved vaccine to prevent RSV in infants
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AAP Guidance and PCA Member Savings on Enflonsia
The American Academy of Pediatrics (AAP) recommends Enflonsia be given to all infants < 8 months of age born during or entering their first RSV season if the infant’s mother did not receive Abrysvo during pregnancy, if the mother’s Abrysvo vaccination status is unknown or if the infant was born <14 days after the mother received Abrysvo.
Infants born between April 1 and October 31 should receive a dose of Enflonsia at a well visit in October or November. Offices should work proactively to make sure all patients born between April 1 and October 31 receive Enflonsia at a well-baby visit sometime in October or November. Enflonsia can be given with other immunizations recommended at the patient’s well-baby visits.
Infants born during RSV season (November 1 – March 31) should receive a dose of Enflonsia either in the hospital prior to discharge or at the first well baby visit in the pediatrician’s office.
Providers may adjust the timing of Enflonsia administration based on guidance from public health authorities or regional medical centers, depending on the geographical variation in the RSV season.
SAVE MONEY ON ENFLONSIA
The best possible discount price for Enflonsia is available through PCA’s Merck vaccine program. PCA can offer a discounted price on Enflonsia because we are a physician buying group. To learn more about becoming a PCA member and discounted pricing on Enflonsia, contact us.
If you do not have a Merck account, please get in touch with us, and we will help you set it up. To find more information on Billing and Coding for Enflonsia, please visit the link below.
